Publications
Publications from IIT Kanpur :
*-co-corresponding author, #- Corresponding author
2023
37.Chitral Chatterjee, Gokul Raj Mohan, Hariharan V.C , Bhumika Biswas, Vidya Sundaram, Ashutosh Srivastava and Saravanan Matheshwaran# (2023) Boronic acid derivative inhibits LexA mediated SOS response in Mycobacteria. bioRxiv https://doi.org/10.1101/2023.11.15.567215
36. G. Dhananjay, M Hemlata, Saravanan Matheshwaran and Sivasurender Chandran (2023) Enhanced Activity Reduces the Duration of Intermittent Lévy Walks in Bacterial Turbulence. arXiv:2307.15035.
35. Ritu Gupta , Hariharan V. Chinnasamy , Dipak Sahu , Saravanan Matheshwaran, Chanchal Sow and Prakash Chandra Mondal (2023) Spin-dependent electrified protein interfaces for probing the CISS effect. Journal of Chemical Physics (Accepted). 10.1063/5.0156479
34. Saravanan Matheshwaran, Sidhharth Chopra, Jitendra K Bera rsc. li/dalton
33. Mandeep Kaur, Ritesh Thakare, Arindom Bhattacherya, Prem Anand Murugan, Grace Kaul, Manjulika Shukla,Alok Kr. Singh, Saravanan Matheshwaran,* Sidharth Chopra* and Jitendra K. Bera* (2023) Antimicrobial efficacy of a hemilabile Pt(II)-NHC compound against drug-resistant S. aureus and Enterococcus. Dalton Transactions, 52, 1876-1884 (co-corresponding author)
2022
32. Soneya Majumdar, Umang Gupta, Hariharan Chinnasamy, Sathishkumar Laxmipathy, Saravanan Matheshwaran# (2022) Zn2+ induced conformational change affects the SAM binding in a mycobacterial SAM-dependent methyltransferase. ACS Omega. 7, 35901–35910.
31. Viral Rawat, Sona Tiwari, Shweta Khanna, Umang Gupta, S. N. C. Sridhar, Dharmendra Yadav, Grace Kaul, Abdul Akhir, Deepanshi Saxena, Saravanan Matheshwaran, Sidharth Chopra, Dharmaraja Allimuthu (2022) Nitroisobenzofuranone, a small molecule inhibitor of multidrug-resistant Staphylococcus aureus targets peptidoglycan biosynthesis. Chem. Comm. , 58, 11669–11672.
30. Yaswanth K. Penke,# Premanand Murugan,# Iram Malik, Saravanan Matheshwaran*, Janakarajan Ramkumar, Kamal K. Kar* (2022) Antibacterial (E.coli/S.aureus) and Arsenic (III/V) Remediation Insights in Aqueous Systems onto Heterogeneous metal oxide (Cu0.52Al0.1Fe0.47O4)/rGO: Hybrid An Approach towards Airborne Microbial Degradation. Environmental Science and Pollution Research. https://doi.org/10.1007/s11356-022-22169-8 (co-corresponding author)
29. Akshat Verma, Prem Anand Murugan, Hariharan Vedi Chinnasamy, Abhas Singh and Saravanan Matheshwaran# (2022) Identification and Genome Analysis of an Arsenic-Metabolizing Strain of Citrobacter youngae IITK SM2 in Middle Indo-Gangetic Plain Groundwater. Biomed Research International https://doi.org/10.1155/2022/6384742.
28. Prem Anand Murugan, Manish Kumar Gupta, T. Sabari Sankar, Sivasurender Chandran, and Saravanan Matheshwaran# (2022) NaCl Triggers the Sessile-to-Motile Transition of Bacillus subtilis bioRxiv doi: https://doi.org/10.1101/2022.02.15.480532.
2021
27. Chitral Chatterjee, Soneya Majumdar, Sachin Deshpande, Deepak Pant and Saravanan Matheshwaran# (2021) Real-time kinetic studies of Mycobacterium tuberculosis LexA-DNA interaction. Bioscience Reports BSR20211419. https://doi.org/10.1042/BCJ20210434
2020
26. Irfan Qayoom, Rahul Verma, Prem Anand Murugan, Deepak Bushan Raina, Arun Kumar Teotia, Saravanan Matheshwaran, Nisanth N.Nair, Magnus Tagil, Lars Lidgren, Ashok Kumar (2020) A biphasic nanohydroxyapatite/calcium sulphate carrier containing Rifampicin and Isoniazid for local delivery gives sustained and effective antibiotic release and prevents biofilm formation. Scientific Reports 10, 14128 doi: 10.1038/s41598-020-70726-3.
25. Bhattacharjee, Arjak; Gupta, Anshul; Verma, Madhu; Anand, Murugan; Sengupta, Pradyut; Matheshwaran, Saravanan; Manna, Indranil; Balani, Kantesh (2020) Effect of Zn and Co Doping on Antibacterial Efficacy and Cytocompatibility of Spark Plasma Sintered Hydroxyapatite. Journal of the American Ceramic Society.00:1–11. doi;10.1111/jace.17077.
2019
24. Bhattacharjee, Arjak; Gupta, Anshul; Verma, Madhu; Anand, Murugan; Sengupta, Pradyut; Matheshwaran, Saravanan; Manna, Indranil; Balani, Kantesh (2019) Antibacterial and magnetic response of site-specific cobalt incorporated hydroxyapatite. Ceramic International. 46 (1), 513-522. doi:10.1016/j.ceramint.2019.08.291.
23. Gayen, A, Kumar, D, Saravanan, M; Manabendra C (2019) Unveiling the Modulating Role of Extracellular pH in Permeation and Accumulation of Small Molecules in Subcellular Compartments of Gram-negative Escherichia coli using Nonlinear Spectroscopy. Analytical Chemistry. 91:7662-7671. doi: 10.1021/acs.analchem.9b00574.
22. Sunaina S, Chinchwadkar S, Aher, A Saravanan M, Ravi Manjithaya. (2019) "Exocyst subcomplex functions in autophagosome biogenesis by regulating Atg9 trafficking". Journal of Molecular Biology. 431: 2821-2834. doi: 10.1016/j .jmb.2019.04.048.
21. Arjak Bhattacharjee, Anshul Gupta, Madhu Verma, Prem Anand Murugan, Pradyut Sengupta, Saravanan Matheshwaran, Indranil Manna, Kantesh Balani (2019) Site-specific antibacterial efficacy and cyto/hemo-compatibility of zinc substituted hydroxyapatite. Ceramic International. 45 :12225-12233. doi: 10.1016/j.ceramint.2019.03.132
20. Prem Anand M, Hariharan VC, Shankar H, Singh A, Saravanan Matheshwaran# (2019) Genome Sequence of Bacillus subtilis subsp. subtilis Strain IITK SM1, Isolated from Kitchen Waste Compost. Microbiol Resource Announcement. 8(6). pii: e01330-18. doi: 10.1128/MRA.01330-18. eCollection 2019
2017
19. Sellamuthu Karthi, Rajeswari Mohan, Franscisco, Thangaraj K, Saravanan Matheshwaran, Perumal Varalakshmi and Balasubramaniem Ashokkumar. 3’-UTR polymorphism rs2229611 in the human G6PC1 gene affects mRNA stability and its expression and confers risk for GSD-Ia (2017) Clinica Chimica Acta 471:46-54. doi: 10.1016/j.cca.2017.05.016.
2016
18. Shakambari G, Anand kumar B, Angelaa Lincy M.J, Rai SK, Ahamed TQ, Ashokkumar B, Saravanan M, Mahesh A and Varalakshmi P. Glutaminase free L-asparaginase from a marine isolate Bacillus tequilensis PV9W: production, purification, characterization and its biological applications (2016) RSC Advances .6, 25943-25951.
Publications from Doctoral and Postdoctoral Work
2015
17. Trivedi U, Kaushik S, Kunjadia P, Saravanan M, Nagaraja V, Archana G, Nareshkumar G. Functional expression and purification of Anabaena PCC 7120 XisA protein. (2015) Protein Expression and Purification. 118:64-9. doi: 10.1016/j.pep.2015.09.027.
2012
16. Saravanan M, Wuerges J,Bose D,Cook N,Zhang X and Wigley D B.Interactions between the nucleosome histone core and Arp8 in the INO80 Chromatin Remodelling Complex.(2012) Proceedings of National Academy of Sciences USA.109:20883-20888. doi: 10.1073/pnas.1214735109.
2011
15. Vasu K,Saravanan M and Nagaraja V. Endonuclease Active Site Plasticity Allows DNA Cleavage with Diverse Alkaline Earth andTransition Metal Ions.(2011 ) ACS Chemical Biology,6:934-942. doi: 10.1021/cb200107y.
2010
14. Vasu K,Saravanan M Rajendra B V,and Nagaraja V Generation of a manganese specific restriction endonuclease with nicking activity (2010). Biochemistry 49: 8425–8433. doi: 10.1021/bi101035k.
2009
13. Swapna G, Saravanan M and Nagaraja V. Identification and characterization of Mg2+ binding residues in transactivator protein C of phage Mu.(2009).Biochemistry 48 :2347–2354. doi: 10.1021/bi8022448.
2008
12. Saravanan M,Vasu K and Nagaraja V. Evolution of sequence specificity in a restriction endonuclease.(2008) Proceedings of National Academy of Sciences USA. 105:10344-10347. doi: 10.1073/pnas.0804974105.
11. Vasu K,Saravanan M and Nagaraja V Structural integrity of ββα-Metal finger motif and its effect on stable protein-DNA complex formation in R.KpnI(2008) BBA-Proteins and Proteomics.1784:32320-32326.
2007
10. Saravanan M, Vasu K,Ghosh S and NagarajaV(2007)Two distinct roles for Zn2+ in maintaining structural integrity and induce DNA sequence specificity in a promiscuous endonuclease. Journal of Biological Chemistry. 282:32320-32326.
9. Saravanan M,Vasu K,Kanakaraj R,Rao D N andNagaraja V(2007) DNAbinding and kinetics with R.KpnI reveal lower degree of discrimination at non-canonical sequences Nucleic Acids Research.35:2777-2786.
2004
8. Saravanan M,Bujnicki J.M,Cymerman I.A,Rao D.N. and Nagaraja V.(2004)Type II restriction endonuclease R.KpnI is a member of the HNH nuclease superfamily. Nucleic Acids Research.32:6129-6135.
7. Chandrashekaran S, Saravanan M, Radha DR, Nagaraja V. (2004) Ca2+ mediated site-specific DNA cleavage and suppression of promiscuous activity of KpnI restriction endonuclease. Journal of Biological Chemistry. 279: 49736-40.
2003
6. Saravanan M, Elango K, Chandrashekaran S, Anand N and Nagaraja V (2003) A new type II restriction endonuclease, OfoI from nonheterocystous cyanobacterium Oscillatoria foreaui. Current Science. 85: 188-191 (Cover Page Article).
Patents
Granted
European Patent
5. Zhu Z, Nagaraja V and Saravanan M (2010) European Patent Office EP 1 931773 B1 Title of the Patent “KpnI Restriction endonuclease with reduced star activity” (Date of Patent: 29.12.2010)
USA patent
4. Nagaraja V, Saravanan M and Zhu Z (2010) US Patent Office US 08119382 B2 Title of the patent “Variant of KpnI restriction endonuclease” (Date of Patent: 21.02.2012)
Applied
3. J.K. Bera, Chopra, S, Saravanan M, Kaur, M. Thakare R. Bhattacherya, A and Murugan PA (2019) "Potency of a Platinum-NHC (N-heterocyclic carbene) compound as antibacterial agent targeting drug resistant Staphylococcus aureus" (Indian Patent Application Number: 201911025087).
2. S.K. Misra, A Singh, Saravanan M, Chatterjee N, Pandey P and Hariharan VC. A FORMULATION FOR INHIBITION OF SARS-COV-2 INFECTION AND PROCESS FOR PREPARATION THEREOF (Indian Patent Application Number: 202111033540 A)
Reviews & Book Chapters:
1.Majumdar S, Sing P and Saravanan M* Chapter 1: Functional Genomics Current Developments in Biotechnology and Bioengineering, Book 2: Functional Genomics and Metabolic Engineering ELsevier arXiv:2307.15035